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Ludmila Matyakhina Selected Research

Carney Complex

1/2008Large deletions of the PRKAR1A gene in Carney complex.
9/200617q22-24 chromosomal losses and alterations of protein kinase a subunit expression and activity in adrenocorticotropin-independent macronodular adrenal hyperplasia.
10/2005Molecular and immunohistochemical investigation of protein kinase a regulatory subunit type 1A (PRKAR1A) in odontogenic myxomas.
6/2005A mouse model for the Carney complex tumor syndrome develops neoplasia in cyclic AMP-responsive tissues.
7/2004Cyclical Cushing syndrome presenting in infancy: an early form of primary pigmented nodular adrenocortical disease, or a new entity?
6/2003Molecular cloning, chromosomal localization of human peripheral-type benzodiazepine receptor and PKA regulatory subunit type 1A (PRKAR1A)-associated protein PAP7, and studies in PRKAR1A mutant cells and tissues.
10/2002Regulatory subunit type I-alpha of protein kinase A (PRKAR1A): a tumor-suppressor gene for sporadic thyroid cancer.

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Ludmila Matyakhina Research Topics

Disease

10Neoplasms (Cancer)
02/2008 - 10/2002
7Carney Complex
01/2008 - 10/2002
4Carcinogenesis
09/2007 - 10/2002
4Hyperplasia
09/2006 - 07/2004
2Aneuploidy (Aneuploid)
08/2015 - 02/2008
2Cushing Syndrome
07/2006 - 09/2003
2Acth-Independent Macronodular Adrenal Hyperplasia
07/2004 - 02/2004
1Trisomy (Trisomies)
08/2015
1Turner Syndrome (Turner's Syndrome)
08/2015
1Chromosome Aberrations (Chromosome Abnormalities)
04/2009
1BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
04/2009
1B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
04/2009
1Carney-Stratakis Syndrome
01/2008
1Gastrointestinal Stromal Tumors (Gastrointestinal Stromal Tumor)
01/2008
1Multiple Endocrine Neoplasia (Multiple Endocrine Adenomatosis)
09/2006
1Amyloid Plaque
12/2005
1Myxoma (Myxomas)
10/2005
1Neurilemmoma (Schwannoma)
06/2005
1Hereditary leiomyomatosis and renal cell cancer
06/2005
1Thrombocytopenia (Thrombopenia)
07/2004
1Polyostotic Fibrous Dysplasia (McCune Albright Syndrome)
07/2004
1Hemorrhage
07/2004
1Congenital Heart Defects (Congenital Heart Defect)
07/2004
1Pituitary Neoplasms (Pituitary Adenoma)
01/2004
1Thyroid Neoplasms (Thyroid Cancer)
10/2002
1Anaplastic Thyroid Carcinoma
10/2002
1Chromosomal Instability (Chromosome Stability)
06/2002

Drug/Important Bio-Agent (IBA)

7Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA
02/2008 - 06/2002
7Proteins (Proteins, Gene)FDA Link
02/2008 - 10/2002
4DNA (Deoxyribonucleic Acid)IBA
09/2007 - 07/2004
4Cyclic AMP (AMP, Cyclic)IBA
07/2006 - 10/2002
3Adrenocorticotropic Hormone (ACTH)FDA Link
09/2006 - 02/2004
2Messenger RNA (mRNA)IBA
02/2008 - 01/2008
2Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA
01/2008 - 09/2007
2Cyclic NucleotidesIBA
07/2006 - 10/2002
2Hydrocortisone (Cortisol)FDA LinkGeneric
02/2004 - 09/2003
2Peptides (Polypeptides)IBA
02/2004 - 10/2002
1N-(4-isothiocyanatophenethyl)spiperoneIBA
08/2015
1fludarabineIBA
04/2009
1Cyclophosphamide (Cytoxan)FDA LinkGeneric
04/2009
1Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
01/2008
1Succinate Dehydrogenase (Fumarate Reductase)IBA
01/2008
1Imatinib Mesylate (Gleevec)FDA Link
01/2008
1Tadalafil (Cialis)FDA Link
07/2006
1ElementsIBA
07/2006
1Phosphoric Diester Hydrolases (Phosphodiesterases)IBA
07/2006
1Carrier Proteins (Binding Protein)IBA
07/2006
1Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA
12/2005
1Codon (Codons)IBA
10/2005
1Amino AcidsFDA Link
10/2005
1Fumarate Hydratase (Fumarase)IBA
06/2005
1Phosphotransferases (Kinase)IBA
12/2004
1von Willebrand factor receptor (VWF receptor)IBA
07/2004
1Platelet Membrane GlycoproteinsIBA
07/2004
1von Willebrand FactorIBA
07/2004
1GlucocorticoidsIBA
07/2004
1Hormones (Hormone)IBA
02/2004
1CatecholaminesIBA
02/2004
1Complementary DNA (cDNA)IBA
02/2004
1Vasopressins (Vasopressin)IBA
02/2004
1Growth Hormone (Somatotropin)IBA
01/2004
1ProlactinIBA
01/2004
1Nonsense Codon (Nonsense Mutation)IBA
09/2003
1SteroidsIBA
06/2003

Therapy/Procedure

1Peripheral Blood Stem Cell Transplantation (Peripheral Stem Cell Transplantation)
04/2009
1Stem Cell Transplantation
04/2009
1Adrenalectomy
07/2004